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Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products

Thiamine monophosphate kinase (ThiL) catalyzes the last step of thiamine pyrophosphate (TPP) synthesis, the ATP-dependent phosphorylation of thiamine monophosphate (TMP) to thiamine pyrophosphate. We solved the structure of ThiL from the human pathogen A. baumanii in complex with a pair of substrate...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sullivan, Amy H., Dranow, David M., Horanyi, Peter S., Lorimer, Donald D., Edwards, Thomas E., Abendroth, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416309/
https://ncbi.nlm.nih.gov/pubmed/30867460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40558-x
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