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Formation of the sacrum requires down-regulation of sonic hedgehog signaling in the sacral intervertebral discs

In humans, the sacrum forms an important component of the pelvic arch, and it transfers the weight of the body to the lower limbs. The sacrum is formed by collapse of the intervertebral discs (IVDs) between the five sacral vertebrae during childhood, and their fusion to form a single bone. We show t...

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Bibliografiska uppgifter
I publikationen:Biol Open
Huvudupphovsmän: Bonavita, Raffaella, Vincent, Kathleen, Pinelli, Robert, Dahia, Chitra Lekha
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Ltd 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078355/
https://ncbi.nlm.nih.gov/pubmed/29784673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.035592
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