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Formation of the sacrum requires down-regulation of sonic hedgehog signaling in the sacral intervertebral discs

In humans, the sacrum forms an important component of the pelvic arch, and it transfers the weight of the body to the lower limbs. The sacrum is formed by collapse of the intervertebral discs (IVDs) between the five sacral vertebrae during childhood, and their fusion to form a single bone. We show t...

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Detalles Bibliográficos
Publicado en:Biol Open
Autores principales: Bonavita, Raffaella, Vincent, Kathleen, Pinelli, Robert, Dahia, Chitra Lekha
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078355/
https://ncbi.nlm.nih.gov/pubmed/29784673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.035592
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