Complementary vaccination protocol with dendritic cells pulsed with autologous tumour lysate in patients with resected stage III or IV melanoma: protocol for a phase II randomised trial (ACDC Adjuvant Trial)

INTRODUCTION: Surgery is one of the treatments of choice for patients with a single metastasis from melanoma but is rarely curative. Such patients could potentially benefit from consolidation immunotherapy. Vaccination with dendritic cells (DCs) loaded with tumour antigens elicits a tumour-specific...

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Veröffentlicht in:BMJ Open
Hauptverfasser: Ridolfi, Laura, de Rosa, Francesco, Fiammenghi, Laura, Petrini, Massimiliano, Granato, Anna Maria, Ancarani, Valentina, Pancisi, Elena, Soldati, Valentina, Cassan, Serena, Bulgarelli, Jenny, Riccobon, Angela, Gentili, Giorgia, Nanni, Oriana, Framarini, Massimo, Tauceri, Francesca, Guidoboni, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2018
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078243/
https://ncbi.nlm.nih.gov/pubmed/30082356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-021701
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