Vaccination with autologous dendritic cells loaded with autologous tumor lysate or homogenate combined with immunomodulating radiotherapy and/or preleukapheresis IFN-α in patients with metastatic melanoma: a randomised “proof-of-principle” phase II study

BACKGROUND: Vaccination with dendritic cells (DC) loaded with tumor antigens elicits tumor-specific immune responses capable of killing cancer cells without inducing meaningful side-effects. Patients with advanced melanoma enrolled onto our phase II clinical studies have been treated with autologous...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: de Rosa, Francesco, Ridolfi, Laura, Ridolfi, Ruggero, Gentili, Giorgia, Valmorri, Linda, Nanni, Oriana, Petrini, Massimiliano, Fiammenghi, Laura, Granato, Anna Maria, Ancarani, Valentina, Pancisi, Elena, Soldati, Valentina, Cassan, Serena, Riccobon, Angela, Parisi, Elisabetta, Romeo, Antonino, Turci, Livia, Guidoboni, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223722/
https://ncbi.nlm.nih.gov/pubmed/25053129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-209
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