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Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes

Studies of host genetic determinants of pathogen sequence variations can identify sites of genomic conflicts, by highlighting variants that are implicated in immune response on the host side and adaptive escape on the pathogen side. However, systematic genetic differences in host and pathogen popula...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Naret, Olivier, Chaturvedi, Nimisha, Bartha, Istvan, Hammer, Christian, Fellay, Jacques
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078058/
https://ncbi.nlm.nih.gov/pubmed/30105048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00266
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