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Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes

Studies of host genetic determinants of pathogen sequence variations can identify sites of genomic conflicts, by highlighting variants that are implicated in immune response on the host side and adaptive escape on the pathogen side. However, systematic genetic differences in host and pathogen popula...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Naret, Olivier, Chaturvedi, Nimisha, Bartha, Istvan, Hammer, Christian, Fellay, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078058/
https://ncbi.nlm.nih.gov/pubmed/30105048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00266
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