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Self-organization of a human organizer by combined WNT and NODAL signalling

In amniotes, the development of the primitive streak (PS) and its accompanying “organizer” define the first stages of gastrulation. Despite detailed characterization in model organisms, the analogous human structures remain a mystery. We have previously shown that when stimulated with BMP4, micropat...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Martyn, I., Kanno, T.Y., Ruzo, A., Siggia, E.D., Brivanlou, A.H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077985/
https://ncbi.nlm.nih.gov/pubmed/29795348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0150-y
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