Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans

Genomic imprinting is an epigenetic mechanism leading to parent-of-origin silencing of alleles. So far, the precise number of imprinted regions in humans is uncertain. In this study, we leveraged genome-wide DNA methylation in whole blood measured longitudinally at three time points (birth, childhoo...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Cuellar Partida, Gabriel, Laurin, Charles, Ring, Susan M, Gaunt, Tom R, McRae, Allan F, Visscher, Peter M, Montgomery, Grant W, Martin, Nicholas G, Hemani, Gibran, Suderman, Matthew, Relton, Caroline L, Davey Smith, George, Evans, David M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Association Studies Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077796/
https://ncbi.nlm.nih.gov/pubmed/29860447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy206
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