Trilobatin Protects Against Oxidative Injury in Neuronal PC12 Cells Through Regulating Mitochondrial ROS Homeostasis Mediated by AMPK/Nrf2/Sirt3 Signaling Pathway

Oxidative stress-induced neuronal cell damage is a crucial factor in the pathogenesis of mitochondria-associated neurological diseases. Therefore, elimination of overproduction of mitochondrial reactive oxygen species (mtROS) may be a potential strategy for prevention and treatment of neurological d...

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Udgivet i:Front Mol Neurosci
Main Authors: Gao, Jianmei, Liu, Shuang, Xu, Fan, Liu, Yuangui, Lv, Chun, Deng, Yan, Shi, Jingshan, Gong, Qihai
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077207/
https://ncbi.nlm.nih.gov/pubmed/30104959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00267
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