Trilobatin Protects Against Aβ(25–35)-Induced Hippocampal HT22 Cells Apoptosis Through Mediating ROS/p38/Caspase 3-Dependent Pathway

Emerging evidence reveals that an aberrant accumulation of β-amyloid (Aβ) is the main reason of Alzheimer’s disease (AD) pathogenesis. Thus, inhibition of Aβ-induced neurotoxicity may be promising therapeutic tactics to mitigate AD onset and advance. The development of agent candidates by cultured n...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chen, Nana, Wang, Jiao, He, Yuqi, Xu, Yingshu, Zhang, Yuchuan, Gong, Qihai, Yu, Changyin, Gao, Jianmei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248209/
https://ncbi.nlm.nih.gov/pubmed/32508629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00584
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