C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation

Blood levels of the acute phase reactant C-reactive protein (CRP) are frequently measured as a clinical marker for inflammation, but the biological functions of CRP are still controversial. CRP is a phosphocholine (PC)-binding pentraxin, mainly produced in the liver in response to elevated levels of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Richter, Katrin, Sagawe, Sabrina, Hecker, Andreas, Küllmar, Mira, Askevold, Ingolf, Damm, Jelena, Heldmann, Sarah, Pöhlmann, Michael, Ruhrmann, Sophie, Sander, Michael, Schlüter, Klaus-Dieter, Wilker, Sigrid, König, Inke R., Kummer, Wolfgang, Padberg, Winfried, Hone, Arik J., McIntosh, J. Michael, Zakrzewicz, Anna Teresa, Koch, Christian, Grau, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077200/
https://ncbi.nlm.nih.gov/pubmed/30105015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01604
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