Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch

Skin vaccination using biodegradable microneedle patch (MNP) technology in vaccine delivery is a promising strategy showing significant advantages over conventional flu shots. In this study, we developed an MNP encapsulating a 4M2e-tFliC fusion protein and two types of whole inactivated influenza vi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhu, Wandi, Li, Song, Wang, Chao, Yu, Guoying, Prausnitz, Mark R., Wang, Bao-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077188/
https://ncbi.nlm.nih.gov/pubmed/30105019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01705
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