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γH2AX is immunohistochemically detectable until 7 days after exposure of N-bis (2-hydroxypropyl) nitrosamine (DHPN) in rat lung carcinogenesis

It is known that γH2AX, which is formed when there is a double-strand break in DNA, can act as a sensitive marker of genomic instability. In this experiment, the time-course manner of the expression of γH2AX in the lung was examined in the early phase after treatment with a lung carcinogen, N-bis (2...

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Detalhes bibliográficos
Publicado no:J Toxicol Pathol
Main Authors: Ying, Jane Tey Xin, Yokohira, Masanao, Nakano-Narusawa, Yuko, Yamakawa, Keiko, Hashimoto, Nozomi, Imaida, Katsumi
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society of Toxicologic Pathology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077157/
https://ncbi.nlm.nih.gov/pubmed/30093785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2017-0066
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