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Activation of MEK1/2‐ERK1/2 signaling during NNK‐induced lung carcinogenesis in female A/J mice

The extracellular signal‐regulated kinase 1/2 (ERK1/2) signaling pathway is activated by several growth factors and mitogens, and upregulation has been noted in many human cancers, including examples in the lung. In this study, to study the association of ERK1/2 activation with mutation of Kras enco...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Yamakawa, Keiko, Yokohira, Masanao, Nakano, Yuko, Kishi, Sosuke, Kanie, Shohei, Imaida, Katsumi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864820/
https://ncbi.nlm.nih.gov/pubmed/26864819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.652
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