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Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer
The ability of disseminated cancer cells to evade the immune response is a critical step for efficient metastatic progression. Protection against an immune attack is often provided by the tumor microenvironment that suppresses and excludes cytotoxic CD8(+) T cells. Pancreatic ductal adenocarcinoma (...
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| Опубликовано в: : | Cancer Res |
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| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6076440/ https://ncbi.nlm.nih.gov/pubmed/29789416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3876 |
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