A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein

Current efforts to develop Zika virus (ZIKV) subunit vaccines have been focused on pre-membrane (prM) and envelope (E) proteins, but the role of NS1 in ZIKV-specific immune response and protection is poorly understood. Here, we develop an attenuated recombinant vesicular stomatitis virus (rVSV)-base...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Li, Anzhong, Yu, Jingyou, Lu, Mijia, Ma, Yuanmei, Attia, Zayed, Shan, Chao, Xue, Miaoge, Liang, Xueya, Craig, Kelsey, Makadiya, Nirajkumar, He, Jennifer J., Jennings, Ryan, Shi, Pei-Yong, Peeples, Mark E., Liu, Shan-Lu, Boyaka, Prosper N., Li, Jianrong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076265/
https://ncbi.nlm.nih.gov/pubmed/30076287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05276-4
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