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A widespread alternate form of cap-dependent mRNA translation initiation
Translation initiation of most mammalian mRNAs is mediated by a 5′ cap structure that binds eukaryotic initiation factor 4E (eIF4E). However, inactivation of eIF4E does not impair translation of many capped mRNAs, suggesting an unknown alternate mechanism may exist for cap-dependent but eIF4E-indepe...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6076257/ https://ncbi.nlm.nih.gov/pubmed/30076308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05539-0 |
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