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Autotaxin exacerbates tumor progression by enhancing MEK1 and overriding the function of miR-489-3p

Upregulated expression of autotaxin, a secreted phospholipase and phosphodiesterase enzyme, appears in malignant disease. The identification of a circulating miRNA signature should distinguish autotaxin-mediated disease and also elucidate unknown molecular mechanisms that rationalize its malignant p...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Kuppa, Sudeepti S., Jia, Wei, Liu, Shuying, Nguyen, Ha, Smyth, Susan S., Mills, Gordon B., Dobbin, Kevin K., Hardman, William J., Murph, Mandi M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075675/
https://ncbi.nlm.nih.gov/pubmed/29859298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.05.037
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