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Transgenic TBK1 mice have features of normal tension glaucoma
Duplication of the TBK1 gene is associated with 1–2% of normal tension glaucoma, a common cause of vision loss and blindness that occurs without grossly abnormal intraocular pressure. We generated a transgenic mouse that has one copy of the human TBK1 gene (native promoter and gene structure) incorp...
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| Udgivet i: | Hum Mol Genet |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6075615/ https://ncbi.nlm.nih.gov/pubmed/28025332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw372 |
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