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Transgenic TBK1 mice have features of normal tension glaucoma

Duplication of the TBK1 gene is associated with 1–2% of normal tension glaucoma, a common cause of vision loss and blindness that occurs without grossly abnormal intraocular pressure. We generated a transgenic mouse that has one copy of the human TBK1 gene (native promoter and gene structure) incorp...

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Bibliografische gegevens
Gepubliceerd in:Hum Mol Genet
Hoofdauteurs: Fingert, John H., Miller, Kathy, Hedberg-Buenz, Adam, Roos, Ben R., Lewis, Carly J., Mullins, Robert F., Anderson, Michael G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075615/
https://ncbi.nlm.nih.gov/pubmed/28025332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw372
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