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Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function

Inactivating mutations in the Armadillo repeat-containing 5 (ARMC5) gene have recently been discovered in primary macronodular adrenal hyperplasia (PMAH), a cause of Cushing syndrome. Biallelic ARMC5 inactivation in PMAH suggested that ARMC5 may have tumor suppressor functions in the adrenal cortex....

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Mol Genet
Egile Nagusiak: Berthon, A., Faucz, F.R., Espiard, S., Drougat, L., Bertherat, J., Stratakis, C.A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074838/
https://ncbi.nlm.nih.gov/pubmed/28911199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx235
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