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A pathogenic PSEN2 p.His169Asn mutation associated with early-onset Alzheimer’s disease
BACKGROUND: Autosomal dominant early-onset Alzheimer’s disease (EOAD) is genetically heterogeneous and has been associated with mutations in 3 different genes, coding for amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2). Most frequent cases are associated with mutation...
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| Publicado no: | Clin Interv Aging |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6074827/ https://ncbi.nlm.nih.gov/pubmed/30104866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S170374 |
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