Impact of exercise on oocyte quality in the POLG mitochondrial DNA mutator mouse

The mtDNA ‘mutator’ mouse, also called the ‘POLG’ mouse, is a well-characterized model frequently used for studies of progeroid aging. Harboring a mutation in the proofreading domain of the mitochondrial polymerase, polymerase-γ (Polg), POLG mice acquire mtDNA mutations at an accelerated rate. This...

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Bibliografske podrobnosti
izdano v:Reproduction
Main Authors: Faraci, Christine, Annis, Sofia, Jin, Joyce, Li, Housaiyin, Khrapko, Konstantin, Woods, Dori C
Format: Artigo
Jezik:Inglês
Izdano: Bioscientifica Ltd 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074767/
https://ncbi.nlm.nih.gov/pubmed/29875308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-18-0061
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