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Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4)

PURPOSE: Citrullination is a post-translational modification (PTM) that serves many normal physiological functions. Studies have shown that this PTM—along with expression of the catalyzing enzymes, peptidyl arginine deiminases (PADs)—are increased in autoimmune and age-related pathologies. PAD2 reti...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Hollingsworth, T. J., Radic, Marko Z., Beranova-Giorgianni, Sarka, Giorgianni, Francesco, Wang, Yanming, Iannaccone, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074612/
https://ncbi.nlm.nih.gov/pubmed/30073354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-24118
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