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Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands
The 11-member APOBEC (apolipoprotein B mRNA editing catalytic polypeptide-like) family of zinc-dependent cytidine deaminases bind to RNA and single-stranded DNA (ssDNA) and, in specific contexts, modify select (deoxy)cytidines to (deoxy)uridines. In this review, we describe advances made through hig...
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| Publicado no: | Trends Biochem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Trends Journals
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6073885/ https://ncbi.nlm.nih.gov/pubmed/29803538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.04.013 |
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