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Involvement of Allosteric Effect and K(Ca) Channels in Crosstalk between β(2)-Adrenergic and Muscarinic M(2) Receptors in Airway Smooth Muscle

To advance the development of bronchodilators for asthma and chronic obstructive pulmonary disease (COPD), this study was designed to investigate the mechanism of functional antagonism between β(2)-adrenergic and muscarinic M(2) receptors, focusing on allosteric effects and G proteins/ion channels c...

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Foilsithe in:Int J Mol Sci
Main Authors: Kume, Hiroaki, Nishiyama, Osamu, Isoya, Takaaki, Higashimoto, Yuji, Tohda, Yuji, Noda, Yukihiro
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073859/
https://ncbi.nlm.nih.gov/pubmed/29987243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071999
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