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Involvement of Allosteric Effect and K(Ca) Channels in Crosstalk between β(2)-Adrenergic and Muscarinic M(2) Receptors in Airway Smooth Muscle

To advance the development of bronchodilators for asthma and chronic obstructive pulmonary disease (COPD), this study was designed to investigate the mechanism of functional antagonism between β(2)-adrenergic and muscarinic M(2) receptors, focusing on allosteric effects and G proteins/ion channels c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kume, Hiroaki, Nishiyama, Osamu, Isoya, Takaaki, Higashimoto, Yuji, Tohda, Yuji, Noda, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073859/
https://ncbi.nlm.nih.gov/pubmed/29987243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071999
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