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Involvement of Allosteric Effect and K(Ca) Channels in Crosstalk between β(2)-Adrenergic and Muscarinic M(2) Receptors in Airway Smooth Muscle

To advance the development of bronchodilators for asthma and chronic obstructive pulmonary disease (COPD), this study was designed to investigate the mechanism of functional antagonism between β(2)-adrenergic and muscarinic M(2) receptors, focusing on allosteric effects and G proteins/ion channels c...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kume, Hiroaki, Nishiyama, Osamu, Isoya, Takaaki, Higashimoto, Yuji, Tohda, Yuji, Noda, Yukihiro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073859/
https://ncbi.nlm.nih.gov/pubmed/29987243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071999
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