Involvement of Ca(2+) Signaling in the Synergistic Effects between Muscarinic Receptor Antagonists and β(2)-Adrenoceptor Agonists in Airway Smooth Muscle

Long-acting muscarinic antagonists (LAMAs) and short-acting β(2)-adrenoceptor agonists (SABAs) play important roles in remedy for COPD. To propel a translational research for development of bronchodilator therapy, synergistic effects between SABAs with LAMAs were examined focused on Ca(2+) signaling...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Fukunaga, Kentaro, Kume, Hiroaki, Oguma, Tetsuya, Shigemori, Wataru, Tohda, Yuji, Ogawa, Emiko, Nakano, Yasutaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037855/
https://ncbi.nlm.nih.gov/pubmed/27657061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17091590
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