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Phosphokinome Analysis of Barth Syndrome Lymphoblasts Identify Novel Targets in the Pathophysiology of the Disease

Barth Syndrome (BTHS) is a rare X-linked genetic disease in which the specific biochemical deficit is a reduction in the mitochondrial phospholipid cardiolipin (CL) as a result of a mutation in the CL transacylase tafazzin. We compared the phosphokinome profile in Epstein-Barr-virus-transformed lymp...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Agarwal, Prasoon, Cole, Laura K., Chandrakumar, Abin, Hauff, Kristin D., Ravandi, Amir, Dolinsky, Vernon W., Hatch, Grant M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073761/
https://ncbi.nlm.nih.gov/pubmed/30002286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19072026
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