The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice

Peroxisome proliferator-activated receptor α (PPARα) is a therapeutic target for hyperlipidemia. Pemafibrate (K-877) is a new selective PPARα modulator activating PPARα transcriptional activity. To determine the effects of pemafibrate on diet-induced obesity, wild-type mice were fed a high-fat diet...

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Pubblicato in:Int J Mol Sci
Autori principali: Araki, Masaya, Nakagawa, Yoshimi, Oishi, Asayo, Han, Song-iee, Wang, Yunong, Kumagai, Kae, Ohno, Hiroshi, Mizunoe, Yuhei, Iwasaki, Hitoshi, Sekiya, Motohiro, Matsuzaka, Takashi, Shimano, Hitoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073532/
https://ncbi.nlm.nih.gov/pubmed/30041488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19072148
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