TNF-α increases the intrinsic excitability of cerebellar Purkinje cells through elevating glutamate release in Bergmann Glia

For decades, the glial function has been highlighted not only as the ‘structural glue’, but also as an ‘active participant’ in neural circuits. Here, we suggest that tumor necrosis factor α (TNF-α), a key inflammatory cytokine, alters the neural activity of the cerebellar Purkinje cells (PCs) by fac...

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Publicado en:Sci Rep
Main Authors: Shim, Hyun Geun, Jang, Sung-Soo, Kim, Seung Ha, Hwang, Eun Mi, Min, Joo Ok, Kim, Hye Yun, Kim, Yoo Sung, Ryu, Changhyeon, Chung, Geehoon, Kim, YoungSoo, Yoon, Bo-Eun, Kim, Sang Jeong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072779/
https://ncbi.nlm.nih.gov/pubmed/30072733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29786-9
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