Butyrate Suppresses the Proliferation of Colorectal Cancer Cells via Targeting Pyruvate Kinase M2 and Metabolic Reprogramming

Butyrate is a short chain fatty acid present in a high concentration in the gut lumen. It has been well documented that butyrate, by serving as an energetic metabolite, promotes the proliferation of normal colonocytes while, by serving as a histone deacetylase inhibitor, epigenetically suppressing t...

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Publicat a:Mol Cell Proteomics
Autors principals: Li, Qingran, Cao, Lijuan, Tian, Yang, Zhang, Pei, Ding, Chujie, Lu, Wenjie, Jia, Chenxi, Shao, Chang, Liu, Wenyue, Wang, Dong, Ye, Hui, Hao, Haiping
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072541/
https://ncbi.nlm.nih.gov/pubmed/29739823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000752
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