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T- and B-cell immunosuppressive activity of novel α-santonin analogs with humoral and cellular immune response in Balb/c mice

In continuation of our endeavours to synthesize immunosuppressive agents from α-santonin, we report herein the design and synthesis of a new series of α-santonin derived O-aryl/aliphatic ether, ester and amide analogs and the evaluation of their immunosuppressive activities. The in vitro studies led...

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Détails bibliographiques
Publié dans:Medchemcomm
Auteurs principaux: Dangroo, Nisar A., Singh, Jasvinder, Gupta, Nidhi, Singh, Shashank, Kaul, Anapurna, Khuroo, Mohmmed A., Sangwan, Payare L.
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072515/
https://ncbi.nlm.nih.gov/pubmed/30108707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00527f
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