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Recovery of humoral and cellular immunity by soluble mediators after 5-fluorouracil-induced immunosuppression.

5-Fluorouracil (5-FU) administered in daily injections to mice (15-60 mg/kg; subcutaneous) was differentially toxic to helper T cells. Precursors for both antibody forming cells and cytotoxic T lymphocytes (CTL) were spared. 5-FU suppressed the in vitro T cell-dependent antibody response to sheep re...

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Detalhes bibliográficos
Main Authors: Merluzzi, V J, Last-Barney, K, Susskind, B M, Faanes, R B
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536680/
https://ncbi.nlm.nih.gov/pubmed/6217933
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