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Mitochondria-targeted betulinic and ursolic acid derivatives: synthesis and anticancer activity
A series of new betulinic and ursolic acid conjugates with a lipophilic triphenylphosphonium cation, meant to enhance the bioavailability and mitochondriotropic action of natural triterpenes, have been synthesized. The in vitro experiments on three human cancer cell lines (MCF-7, HCT-116 and TET21N)...
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| Pubblicato in: | Medchemcomm |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072465/ https://ncbi.nlm.nih.gov/pubmed/30108714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00248c |
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