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Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids

Acetaminophen (APAP) is possibly the most widely used medication globally and yet little is known of its molecular effects at therapeutic doses. Using a novel approach, we have analysed the redox proteome of the hepatocellular cell line HepG2/C3A treated with therapeutic doses of APAP and quantitate...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Wojdyla, Katarzyna, Wrzesinski, Krzysztof, Williamson, James, Fey, Stephen J., Rogowska-Wrzesinska, Adelina
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072433/
https://ncbi.nlm.nih.gov/pubmed/30090399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00469a
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