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Designing safer oral drugs
Designing an oral drug such that its estimated dose to humans is both efficacious and safe is challenging. During the early design stage, where in vitro or preclinical species in vivo safety data are limited, heuristic-based criteria often related to physicochemical properties are used for guidance....
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| Publicado en: | Medchemcomm |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072361/ https://ncbi.nlm.nih.gov/pubmed/30108773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00706f |
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