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Synthesis of benzo[d]thiazole-hydrazone analogues: molecular docking and SAR studies of potential H(+)/K(+) ATPase inhibitors and anti-inflammatory agents

A series of new benzo[d]thiazole-hydrazones were synthesized and characterized by analytical and spectroscopic techniques. All the compounds were screened for their in vitro inhibition of H(+)/K(+) ATPase and anti-inflammatory effects. The results revealed that compounds 6–8, 13–15, 18–20, 22, 23 an...

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Dettagli Bibliografici
Pubblicato in:Medchemcomm
Autori principali: Wang, Shi-Meng, Zha, Gao-Feng, Rakesh, K. P., Darshini, N., Shubhavathi, T., Vivek, H. K., Mallesha, N., Qin, Hua-Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072339/
https://ncbi.nlm.nih.gov/pubmed/30108827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00111h
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