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Tumor cell resistance against targeted therapeutics: the density of cultured glioma tumor cells enhances Stat3 activity and offers protection against the tyrosine kinase inhibitor canertinib

Tumor cell resistance to drug treatment severely limits the therapeutic success of treatment. Tumor cells, exposed to chemotherapeutic drugs, have developed intricate strategies to escape the cytotoxic effects and adapt to adverse conditions. The molecular mechanisms causing drug resistance can be b...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: von Manstein, V., Groner, B.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072326/
https://ncbi.nlm.nih.gov/pubmed/30108694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00463f
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