A Combination of Two Receptor Tyrosine Kinase Inhibitors, Canertinib and PHA665752 Compromises Ovarian Cancer Cell Growth in 3D Cell Models

INTRODUCTION: Advanced ovarian cancer is often a fatal disease as chemotherapeutic drugs have limited effectiveness. Better targeted therapy is needed to improve the survival and quality of life for these women. Receptor tyrosine kinases including EGFR, Her-2 and c-Met are associated with a poor pro...

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Vydáno v:Oncol Ther
Hlavní autoři: Hassan, Wafaa, Chitcholtan, Kenny, Sykes, Peter, Garrill, Ashley
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Healthcare 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315083/
https://ncbi.nlm.nih.gov/pubmed/28261654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40487-016-0031-1
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