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Sclerostin is upregulated in the early stage of chondrogenic differentiation, but not required in endochondral ossification in vitro
Sclerostin is a potent inhibitor of the canonical Wnt signaling pathway. Wnt signaling pathways have multiple roles in the regulation of cartilage development, growth, and maintenance. This study focused on the role of sclerostin in the process of chondrogenic differentiation. We hypothesized that s...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072128/ https://ncbi.nlm.nih.gov/pubmed/30071108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201839 |
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