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Design, synthesis and bioactivity investigation of tetrandrine derivatives as potential anti-cancer agents
Twenty-four 14-sulfonamide–tetrandrine derivatives as potential anti-cancer agents were synthesized. The synthetic derivatives were investigated for their cytotoxic activity against human cancer cell lines MDA-MB-231, PC3, WM9, HEL and K562. Initially, the IC(50) values (50% inhibitory concentration...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072089/ https://ncbi.nlm.nih.gov/pubmed/30109000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00125a |
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