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Long-term stability and computational analysis of migration patterns of L-MYC immortalized neural stem cells in the brain

BACKGROUND: Preclinical studies indicate that neural stem cells (NSCs) can limit or reverse central nervous system (CNS) damage through delivery of therapeutic agents for cell regeneration. Clinical translation of cell-based therapies raises concerns about long-term stability, differentiation and fa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rockne, Russell C., Adhikarla, Vikram, Tsaturyan, Lusine, Li, Zhongqi, Masihi, Meher B., Aboody, Karen S., Barish, Michael E., Gutova, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071994/
https://ncbi.nlm.nih.gov/pubmed/30071048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199967
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