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Long-term stability and computational analysis of migration patterns of L-MYC immortalized neural stem cells in the brain.

BACKGROUND:Preclinical studies indicate that neural stem cells (NSCs) can limit or reverse central nervous system (CNS) damage through delivery of therapeutic agents for cell regeneration. Clinical translation of cell-based therapies raises concerns about long-term stability, differentiation and fat...

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Detalhes bibliográficos
Main Authors: Russell C Rockne, Vikram Adhikarla, Lusine Tsaturyan, Zhongqi Li, Meher B Masihi, Karen S Aboody, Michael E Barish, Margarita Gutova
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2018-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC6071994?pdf=render
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