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Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories
In cancers, hypoxia inducible factor 1 (HIF-1) is an over-expressed transcription factor, which regulates a large set of genes involved in tumour vascularization, metastases, and cancer stem cells (CSCs) formation and self-renewal. This protein has been identified as a relevant target in oncology an...
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| Publicado no: | Medchemcomm |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071925/ https://ncbi.nlm.nih.gov/pubmed/30108689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00432f |
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