A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate

Diphosphoinositol phosphates (PP-InsPs) are inositol phosphates (InsPs) that contain PP (diphosphate) groups. Converting a phosphate group in an InsP into a diphosphate has been reported to enhance affinity for some binding proteins. We synthesised 1-PP-Ins(4,5)P(2), the first diphosphate analogue o...

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Publicat a:Medchemcomm
Autors principals: Riley, Andrew M., Unterlass, Judith E., Konieczny, Vera, Taylor, Colin W., Helleday, Thomas, Potter, Barry V. L.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2018
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071853/
https://ncbi.nlm.nih.gov/pubmed/30079174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00149a
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