DHX15 regulates CMTR1-dependent gene expression and cell proliferation

CMTR1 contributes to mRNA cap formation by methylating the first transcribed nucleotide ribose at the O-2 position. mRNA cap O-2 methylation has roles in mRNA stabilisation and translation, and self-RNA tolerance in innate immunity. We report that CMTR1 is recruited to serine-5–phosphorylated RNA Po...

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Publicat a:Life Sci Alliance
Autors principals: Inesta-Vaquera, Francisco, Chaugule, Viduth K, Galloway, Alison, Chandler, Laurel, Rojas-Fernandez, Alejandro, Weidlich, Simone, Peggie, Mark, Cowling, Victoria H
Format: Artigo
Idioma:Inglês
Publicat: Life Science Alliance LLC 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071836/
https://ncbi.nlm.nih.gov/pubmed/30079402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800092
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