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Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature

Mice lacking perilipin-2 (Plin2-null) are resistant to obesity, insulin resistance, and fatty liver induced by Western or high-fat diets. In the current study, we found that, compared with WT mice on Western diet, Plin2-null adipose tissue was more insulin sensitive and inguinal subcutaneous white a...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Libby, Andrew E., Bales, Elise S., Monks, Jenifer, Orlicky, David J., McManaman, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071773/
https://ncbi.nlm.nih.gov/pubmed/29866659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M086249
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