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Membrane activity profiling of small molecule B. subtilis growth inhibitors utilizing novel duel-dye fluorescence assay

Small molecule disruption of the bacterial membrane is both a challenge and interest for drug development. While some avoid membrane activity due to toxicity issues, others are interested in leveraging the effects for new treatments. Existing assays are available for measuring disruption of membrane...

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Detaylı Bibliyografya
Yayımlandı:Medchemcomm
Asıl Yazarlar: McAuley, S., Huynh, A., Czarny, T. L., Brown, E. D., Nodwell, J. R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071753/
https://ncbi.nlm.nih.gov/pubmed/30108946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00009c
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